To introduce the student to the discipline of industrial biochemistry. To provide the student with a reference framework for future core course modules. To generate student interest and enthusiasm for the subject area by focusing upon relevant, topical issues of broad public interest

Genetic information and genetic engineering; overview of approaches and applications. DNA fingerprinting and its applications. The human genome project and its impact on society. The cloning of mammals. The biochemistry of HIV. Viral structure and biology. Biotechnological approached to developing a cure/vaccine. Prion biology. BSE and CJD. Dangerous microbes; concept of mobile DNA. Molecular biology of cancer. Oncogenes and cellular transformation. Biotech strategies to cure cancer. The approach to research; case studies; identification of a problem, planning and pursuing a research strategy. Evaluating the results. Pharmaceutical biology and biotechnology. Approaches to drug discovery. Products of pharmaceutical biotechnology and their medical uses. Gene medicines. Life at the extremes; the unique biology of hyperthermophiles. Hyperthermophiles as a source in industrially relevant substances. Biological warfare. Practical applications of industrial biochemistry. Review of biochemical processes currently used at an industrial scale. Some fundamental concepts in bioprocess engineering. The role of an industrial biochemist in a process work environment. The spectrum of career choices open to industrial biochemists.

1. Describe some key concepts and practical applications of industrial biochemistry 2. Identify the major career options open to an industrial biochemist 3. Demonstrate an understanding of the fundamental concepts underpinning bioprocess engineering. 4. Outline the basic principles of, and approaches to, undertaking research.

1. Identify and appreciate issues relevant to the public perception of biotechnology

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Module will be taught primiraly through a formal interactive lecturing mode (2 lectures and 1 tutorial per week). The students will also research and prepare an essay focusing upon some relevant aspect of the sullabus. The module will be assessed by means of a final written exam (normally 75% of marks) and essay (normally 25% of marks).

Not applicable